نوع مقاله : پژوهشی
نویسندگان
استاد دانشگاه پیام نور تهران
چکیده
Objective: This study aimed to assess the effectiveness of Cognitive-Behavioral Stress Management (CBSM) on distress tolerance, pain perception, and interleukin-12 (IL-12) in patients with Multiple Sclerosis (MS). Method: The present study was a quasi-experimental design with pretest-posttest and follow-up with control group. The statistical population included all female patients with relapsing-remitting MS who had referred to Neuroscience and Rehabilitation Research Centers of Tehran University of Medical Sciences. 20 patients were selected by convenience sampling and were randomly assigned into experimental (10 patients) and control groups (10 patients). The experimental group received the CBSM. Participants completed scales. To measure IL-12, the Enzyme-Linked Immunosorbent Assay (ELISA) was used. The data were analyzed using multivariate analysis of covariance (MANCOVA) and Bonferroni post-hoc test. Results: CBSM increased the distress tolerance and components of pain perception (perceived influence of important people and doing daily affairs) (p <0.001) and it decreased pain severity and IL-12. Also, these changes remained stable during follow-up. Conclusions: CBSM is an effective to influence on distress tolerance, pain perception, and IL-12 in MS patients.
کلیدواژهها
Abolghasemi, A., Mikaeili, N., Khoshnoodnia Chomachaei, B., & Karimi Yousefi, S. H. (2018). Effectiveness of Cognitive Therapy on Emotional Distress and Stress Coping Strategies in Patients with Multiple Sclerosis. Biquarterly Iranian Journal of Health Psychology, 1(1), 29-36.
Afonina, I. S., & Beyaert, R. (2016). Trabid epigenetically drives expression of IL-12 and IL-23. Nature Immunology, 17(3), 227-228.
Alexander, J. S., Harris, M. K., Wells, S. R., Mills, G., Chalamidas, K., Ganta, V. C., ... & Minagar, A. (2010). Alterations in serum MMP-8, MMP-9, IL-12p40 and IL-23 in multiple sclerosis patients treated with interferon-β1b. Multiple Sclerosis Journal, 16(7), 801-809.
Alschuler, K. N., & Beier, M. L. (2015). Intolerance of uncertainty: shaping an agenda for research on coping with multiple sclerosis. International journal of MS care, 17(4), 153-158.
Anagnostouli, M., Babili, I., Chrousos, G., Artemiadis, A., & Darviri, C. (2019). A novel cognitive-behavioral stress management method for multiple sclerosis. A brief report of an observational study. Neurological Research, 41(3), 223-226.
Antoni, M. H., Ironson, G., & Schneiderman, N. (2007). Cognitive-behavioral stress management. Oxford University Press.
Antoni, M. H., Lechner, S., Diaz, A., Vargas, S., Holley, H., Phillips, K., ... & Blomberg, B. (2009). Cognitive behavioral stress management effects on psychosocial and physiological adaptation in women undergoing treatment for breast cancer. Brain, Behavior, and Immunity, 23(5), 580-591.
Asadbeygi, A., Ahadi, H., & Mirzaei, H. (2019). Assessing the Effectiveness of Cognitive Behavioral Stress Management (CBSM) on Pain Perception of Cancer Patients. Novelty in Biomedicine, 7(3), 130-133.
Asadi Haghighat, M., Zahrakar, K., & Farzad, V. (2019). Cognitive-Behavioral Stress Management Training (CBSM) on Reducing Stress Symptoms of Women with Multiple Sclerosis (MS). Middle Eastern Journal of Disability Studies, 9, 77-77.
Bahrami Rad, M., & Rafezi, Z. (2019). Predicting Pain Acceptance Based on Perceived Stress and Coping Strategies in individuals with Rheumatoid Arthritis. Health Psychology, 7(28), 151-166.
Berk, L. S., Bellinger, D. L., Koenig, H. G., Daher, N., Pearce, M. J., Robins, C. J., ... & King, M. B. (2015). Effects of religious vs. conventional cognitive-behavioral therapy on inflammatory markers and stress hormones in major depression and chronic medical illness: A randomized clinical trial. Open Journal of Psychiatry, 5(03), 238.
Bernstein, I. H., Jaremko, M. E., & Hinkley, B. S. (1995). On the utility of the West Haven-Yale Multidimensional Pain Inventory. Spine, 20(8), 956-963.
Brydon, L., Edwards, S., Mohamed-Ali, V., & Steptoe, A. (2004). Socioeconomic status and stress-induced increases in interleukin-6. Brain, Behavior, and Immunity, 18(3), 281-290.
Burkill, S., Montgomery, S., Kockum, I., Piehl, F., Strid, P., Hillert, J., ... & Bahmanyar, S. (2019). The association between multiple sclerosis and pain medications. Pain, 160(2), 424-432.
Chandola, T., Heraclides, A., & Kumari, M. (2010). Psychophysiological biomarkers of workplace stressors. Neuroscience & Biobehavioral Reviews, 35(1), 51-57.
Chen, H. Y., Cheng, I. C., Pan, Y. J., Chiu, Y. L., Hsu, S. P., Pai, M. F., ... & Wu, K. D. (2011). Cognitive-behavioral therapy for sleep disturbance decreases inflammatory cytokines and oxidative stress in hemodialysis patients. Kidney International, 80(4), 415-422.
Craig, A.W. (2001). Cognitive behaviour therapy for chronic medical problems: a guide to assessment and treatment in practice. 1st ed. Wiley.
Cruess, D. G., Antoni, M. H., Schneiderman, N., Ironson, G., McCabe, P., Fernandez, J. B., ... & Kumar, M. (2000). Cognitive–behavioral stress management increases free testosterone and decreases psychological distress in HIV-seropositive men. Health Psychology, 19(1), 12-20.
De Oliveira, J. F., Wiener, C. D., Jansen, K., Portela, L. V., Lara, D. R., de Mattos Souza, L. D., ... & Oses, J. P. (2018). Serum levels of interleukins IL-6 and IL-10 in individuals with posttraumatic stress disorder in a population-based sample. Psychiatry Research, 260, 111-115.
Ebrahimi, A., & Ghahari, S. (2020). The effectiveness of mindfulness-based stress reduction (MBSR) on anxiety and depression in patients with multiple sclerosis (MS). Chronic Diseases Journal, 8(1), 21-25.
Emami, M., Askarizade, G., & Faziltpour, M. (2017). Effectiveness of cognitive–behavioral stress management group therapy on resilience and hope in women with breast cancer. Positive Psychology, 4(12), 1-13.
Felton, J. W., Banducci, A. N., Shadur, J. M., Stadnik, R., MacPherson, L., & Lejuez, C. W. (2017). The developmental trajectory of perceived stress mediates the relations between distress tolerance and internalizing symptoms among youth. Development and Psychopathology, 1-11.
Habibi, J., Habibi, A., Malekzadeh Moghani, M., Ghanbari, N. (2013). The effectiveness of cognitive-behavioral stress management on the level of distress tolerance of women with cancer. 9th International Breast Cancer Congress.
Hall, D. L. (2016). Effects of telephone-delivered cognitive behavioral stress management intervention on fatigue interference and neuroimmune function in chronic fatigue syndrome (Doctoral dissertation, University of Miami).
Hasanzadeh Pashang, S., Zare, H., & Alipor, A. (2012). The efficacy of stress inculation training (SIT) on resilience, anxiety, depression and stress among spinal cord injury (SCI) patients. Pars Medical Sciences Journal, 10 (3), 15-26.
Hayek, S., Brinkman, T. M., Plana, J. C., Joshi, V. M., Leupker, R. V., Durand, J. B., ... & Srivastava, D. K. (2020). Association of Exercise Intolerance with Emotional Distress, Attainment of Social Roles, and Health-Related Quality of Life Among Adult Survivors of Childhood Cancer. JAMA Oncology. 1-13.
Heffer-Rahn, P., & Fisher, P. L. (2018). The clinical utility of metacognitive beliefs and processes in emotional distress in people with multiple sclerosis. Journal of Psychosomatic Research, 104, 88-94.
Heitmann, H., Haller, B., Tiemann, L., Mühlau, M., Berthele, A., Tölle, T. R., ... & Hartung, H. P. (2020). Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study. Pain, 161(4), 787-796.
Irwin, M. R., Olmstead, R., Breen, E. C., Witarama, T., Carrillo, C., Sadeghi, N., & Cole, S. (2015). Cognitive behavioral therapy and tai chi reverse cellular and genomic markers of inflammation in late-life insomnia: a randomized controlled trial. Biological Psychiatry, 78(10), 721-729.
Jandoghi, F., Neshatdoost, HT., Kalantari, M., & Jabal Ameli, S. (1391). Study of the effectiveness of group training on cognitive-behavioral stress management on anxiety and depression in people with substance abuse under methadone maintenance therapy. Clinical Psychology, 4 (16), 50-41.
Javanmard, G. H., & Goli, F. (2018). The effectiveness of mindfulness-based stress reduction on negative emotions about disease’s signs in patients with gastrointestinal disorders. Biquarterly Iranian Journal of Health Psychology, 1(2), 73-82.
Jones, M. E., Lebonville, C. L., Paniccia, J. E., Balentine, M. E., Reissner, K. J., & Lysle, D. T. (2018). Hippocampal interleukin-1 mediates stress-enhanced fear learning: A potential role for astrocyte-derived interleukin-1β. Brain, Behavior, and Immunity, 67, 355-363.
Joseph, J. P. (2019). Diagnosis of Multiple Sclerosis. In Multiple Sclerosis. IntechOpen.
Kafaki, H. B., Moafi, M., Golestani, R., Bekineh, F., & Ebrahimi, S. M. H. S. (2017). The Effect of Short-Term Solution Focused Therapy on Distress Tolerance and Social Adjustment of Patients with MS in Sari. American Journal of Applied Psychology, 6(6), 147-152.
Kallaur, A. P., Oliveira, S. R., Alfieri, D. F., Flauzino, T., Lopes, J., Pereira, W. L. D. C. J., ... & Reiche, E. M. V. (2017). Cytokine profile in patients with progressive multiple sclerosis and its association with disease progression and disability. Molecular neurobiology, 54(4), 2950-2960.
Kim, J. A., Bosma, R. B., Hemington, K. S., Rogachov, A., Osborne, N. R., Cheng, J. C., ... & Davis, K. D. (2020). Cross-network coupling of neural oscillations in the dynamic pain connectome reflects chronic neuropathic pain in multiple sclerosis. NeuroImage: Clinical, 102230.
Kim, Y. K., Suh, I. B., Kim, H., Han, C. S., Lim, C. S., Choi, S. H., & Licinio, J. (2002). The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: effects of psychotropic drugs. Molecular Psychiatry, 7(10), 1107.
Lattie, E. G. (2015). The Effects of Telephone-Delivered Cognitive Behavioral Stress Management on Inflammation and Symptoms in Myalgic Enchephalomyelitis/Chronic Fatigue Syndrome: A Computational Immunology Approach (Doctoral dissertation). University of Miami Scholarly Repository.
Levenstein, S., Prantera, C., Varvo, V., Scribano, M. L., Andreoli, A., Luzi, C., ... & Marcheggiano, A. (2000). Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. The American Journal of Gastroenterology, 95(5), 1213-1220.
Losy, J., & Michałowska‐Wender, G. (2002). In vivo effect of interferon‐β 1a on interleukin‐12 and TGF‐β1 cytokines in patients with relapsing–remitting multiple sclerosis. Acta Neurologica Scandinavica, 106(1), 44-46.
Lovett-Racke, A. E., & Racke, M. K. (2018). Role of IL-12/IL-23 in the Pathogenesis of Multiple Sclerosis. In Neuroinflammation (pp. 115-139). Academic Press.
Marsland, A. L., Walsh, C., Lockwood, K., & John-Henderson, N. A. (2017). The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis. Brain, Behavior, and Immunity, 64, 208-219.
Mawdsley, J. E., & Rampton, D. S. (2005). Psychological stress in IBD: new insights into pathogenic and therapeutic implications. Gut, 54(10), 1481-1491.
Melzack, R., & Wall, P. D. (2016). Interaction of fast and slow conducting fibre systems involved in pain and analgesia. Proc. 3rd Int. Pharm. Meet, 9, 231-242.
Mirzamani, S.M., Safari, A., Hali Saz, M.T., Sadidi, A. (2006). Assessing the validity of the West Hoon-Yale multidimensional pain questionnaire among patients with chronic pain. Journal of Qom University of Medical Sciences, 1 (3): 25-13.
Mohammadi, N., Aghaei, A., Golparuz, M., & Etemadifar, M. (2007). The effect of cognitive-behavioral group training on the stress of patients with multiple sclerosis. Knowledge and Research in Psychology, 16-1.
Montazeri-Khadem, V., Jabbari, Z., Shahriari, M., Hagayegh, S. A., & Hashemi, H. (2016). Effectiveness of stress management cognitive-behavioral therapy on psychological and physiological indexes of mothers volunteer to cesarean surgery. Journal of Research Behavioral Science, 14(2), 229-235.
Moreira, F. P., de Azevedo Cardoso, T., Mondin, T. C., de Mattos Souza, L. D., Silva, R., Jansen, K., ... & Wiener, C. D. (2015). The effect of proinflammatory cytokines in Cognitive Behavioral Therapy. Journal of Neuroimmunology, 285, 143-146.
Nazemi, F., Bahrami Ehsan, H., Alipour, A., & Bayat, N. (2018). Efficacy of Stress Management Intervention on Psychological, Immune Factors and Pain in Rheumatoid Arthritis Patients. Biquarterly Iranian Journal of Health Psychology, 1(2), 33-44.
Nejatpour, S., Fathei, M., & Yaghoubi, A. (2019). The effect of aqua-therapy on plasma and interleukin-12 and 17 in patients with multiple sclerosis. Sport TK: revista euroamericana de ciencias del deporte, 8(1), 89-94.
Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., ... & Zonin, F. (2000). Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity, 13(5), 715-725.
Reynard, A. K., Sullivan, A. B., & Rae-Grant, A. (2014). A systematic review of stress-management interventions for multiple sclerosis patients. International Journal of MS Care, 16(3), 140-144.
Sanagoie Mohrar, G., & Hosseinzadeh, M, (2017). Investigating the relationship between emotional self-regulation and distress tolerance and quality of life of MS Society (a case study of MS patients in Sistan and Baluchestan province). Social Science Studies Quarterly, 3 (2): 203-196.
Shams, J., Azizi, A., & Mirzaei, A. (2010). Investigating the relationship between tolerance of confusion and emotional regulation with the degree of students' dependence on smoking. Hakim Health System Research Journal, 13 (1), 18-11.
Sheibani, F. (2018). Comparison of the effectiveness of group mindfulness intervention based on stress reduction and group intervention of cognitive-behavioral stress management on biological indicators and psychological symptoms of patients with major hypertension. PhD Thesis, Clinical Psychology, Iran University of Medical Sciences.
Shokouhiyekta, M., & Parand, A. (2012). Strategies for stress management. Sepidbarg Publication.
Simons, J. S & Gaher, R.M. (2005). The distress tolerance scale: Development& validation of a self report measure. Motivation & Emotion, 20(9), 83- 102.
Song, C., Li, X., Leonard, B. E., & Horrobin, D. F. (2003). Effects of dietary n-3 or n-6 fatty acids on interleukin-1β-induced anxiety, stress, and inflammatory responses in rats. Journal of Lipid Research, 44(10), 1984-1991.
Sparaco, M., Lavorgna, L., & Bonavita, S. (2019). Psychiatric disorders in multiple sclerosis. Journal of neurology, 1-16.
Steptoe, A., Hamer, M., & Chida, Y. (2007). The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain, Behavior, and Immunity, 21(7), 901-912.
Tarlinton, R., Morandi, E., Wang, B., Gran, B., Khaiboullin, T., Martynova, E., ... & Khaiboullina, S. (2020). Viruses in multiple sclerosis pathogenesis. Access Microbiology, 2(6), 643.
Taub, C., Fisher, H., Amiel, C., Jutagir, D., Bouchard, L., Gudenkauf, L., ... & Antoni, M. (2017). Baseline pain intensity and pain interference moderate effects of cognitive behavioral stress management on leukocyte inflammatory gene expression in women with breast cancer. The Journal of Pain, 18(4), S81.
Taylor, P., Dorstyn, D. S., & Prior, E. (2020). Stress management interventions for multiple sclerosis: A meta-analysis of randomized controlled trials. Journal of Health Psychology, 25(2), 266-279.
Van Boxel-Dezaire, A. H. H., van Trigt-Hoff, S. C. J., Killestein, J., Schrijver, H. M., Van Houwelingen, J. C., Polman, C. H., & Nagelkerken, L. (2000). Contrasting responses to interferon β-1 b treatment in relapsing-remitting multiple sclerosis: Does baseline interleukin-12 p 35 messenger RNA predict the efficacy of treatment?. Annals of Neurology, 48(3), 313-322.
Yusuf, F. L., Wijnands, J. M., Kingwell, E., Zhu, F., Evans, C., Fisk, J. D., ... & Tremlett, H. (2020). Fatigue, sleep disorders, anaemia and pain in the multiple sclerosis prodrome. Multiple Sclerosis Journal, 1352458520908163.
)