In collaboration with Payame Noor University and Iranian Health Psychology

Document Type : review


shahid beheshti university


Objective: Pathogen disgust has evolved as a psychological adaptation in response to the avoidance of disease-causing organisms. Recently, evolutionary social psychologists have proposed the existence of a behavioral immune system that has evolved to avoid pathogens as a psychological adaptation. However, researchers claim that the concept of a behavioral immune system is not the same as pathogen avoidance. Therefore, in this study, the aim is to investigate whether the behavioral immune system is the same as the pathogen avoidance system or has a broader meaning.
Method: Using the Google Scholar database, keywords such as disease avoidance, pathogen disgust, and the behavioral immune system were searched. PubMed for the behavioral immune system, system over perception disease cues, and disease over perception bias was investigated as well. All-time periods were used for this review study and more than two hundred documents were reviewed and extracted according to the criteria.
Results: The findings show that there are three main mechanisms involved in the behavioral immune system. This system includes emotional, cognitive, and behavioral mechanisms. Therefore, the results showed that the behavioral immune system has a broader meaning than the pathogen avoidance system.
Conclusion: Research on physiological correlations with emotional experiences shows that disgust is evoked in response to pathogen-related stimuli and is associated with unique patterns of the autonomic nervous system and neural activity. However little is known about the functional connections between anatomical structures, neurochemical processes, and various cognitive and behavioral phenomena that are the manifestations of the behavioral immune system, and more studies are needed in this area.


Article Title [Persian]

مروری بر تشخیص پاتوژن ها از طریق سیستم ایمنی رفتاری

Author [Persian]

  • آسیه افتخاری

دانشگاه شهید بهشتی

Abstract [Persian]

هدف: انزجاراز پاتوژن به عنوان یک سازگاری روانشناختی در پاسخ به جلوگیری از ارگانیسم های عامل بیماری تکامل یافته است. اخیراً ، روانشناسان اجتماعی تکاملی وجود یک سیستم ایمنی رفتاری را پیشنهاد داده اند که برای جلوگیری از عوامل بیماری زا به عنوان یک سازگاری روانشناختی تکامل یافته است. با این حال ، محققان ادعا می کنند که مفهوم سیستم ایمنی رفتاری همان اجتناب از عوامل بیماری زا نیست. بنابراین ، در این مطالعه ، این مسئله بررسی می شود که آیا سیستم ایمنی رفتاری همان سیستم اجتناب از پاتوژن است یا معنای وسیع تری دارد.
روش: با استفاده از کلمات کلیدی پایگاه داده Google Scholar مانند اجتناب از بیماری ، انزجار از عوامل بیماری زا ، سیستم ایمنی رفتاری جستجو شد. PubMed برای سیستم ایمنی رفتاری ، سیستم ادراک بیش از حد علائم مورد بررسی قرار گرفت. از تمام بازه های زمانی برای این مطالعه مروری استفاده شد و بیش از دویست سند با توجه به معیارهای بررسی و استخراج شد.
یافته ها: یافته ها نشان می دهد که سه مکانیسم اصلی در سیستم ایمنی رفتاری دخیل هستند. این سیستم ها شامل سیستم های عاطفی ، شناختی و رفتاری هستند.
نتیجه گیری: تحقیقات در مورد ارتباطات فیزیولوژیکی با تجربیات عاطفی نشان می دهد که انزجار در پاسخ به محرکهای مرتبط با پاتوژن برانگیخته می شود و با الگوهای منحصر به فرد فعالیت سیستم عصبی خودمختار و فعالیت عصبی همراه است. اما اطلاعات کمی در مورد ارتباطات عملکردی بین ساختارهای آناتومیکی ، فرایندهای عصبی شیمیایی و پدیده های مختلف شناختی و رفتاری که مظاهر سیستم ایمنی رفتاری هستند ، وجود دارد و مطالعات بیشتری در این زمینه مورد نیاز است.

Keywords [Persian]

  • سیستم ایمنی
  • اجتناب
  • انزجار
Ackerman, J. M., Becker, D. V., Mortensen, C. R., Sasaki, T., Neuberg, S. L., & Kenrick, D. T. (2009). A pox on the mind: Disjunction of attention and memory in the processing of physical disfigurement. Journal of Experimental Social Psychology, 45(3), 47-48.    
Aliakbari Dehkordi, M., Mohtashami, T., & Tabrizi, T. (2020). Developing, validity and validated Lifestyle Scale During COVID-19 Disease Pandemic. Quarterly Journal of Health Psychology, 9(33), 161-177
Armstrong, T., Engel, M., Press, T., Sonstroem, A., & Reed, J. (2019). Fast-forwarding disgust conditioning: US pre-exposure facilitates the acquisition of oculomotor avoidance. Motivation and Emotion, 43(4), 681-695.         
Brown, M., Keefer, L. A., Sacco, D. F., & Bermond, A. (2019). Is the cure a wall? Behavioral immune system responses to a disease metaphor for immigration. Evolutionary Psychological Science, 5(3), 343-356.    
Clay, R. (2017). The behavioral immune system and attitudes about vaccines: contamination aversion predicts more negative vaccine attitudes. Social Psychological and Personality Science, 8(2), 162-172.
Culpepper, P. D., Havlíček, J., Leongómez, J. D., & Roberts, S. C. (2018). Visually activating pathogen disgust: a new instrument for studying the behavioral immune system. Frontiers in psychology, 9, 1397.          
Curtis, V., Aunger, R., & Rabie, T. (2004). Evidence that disgust evolved to protect from risk of disease. Proceedings of the Royal Society of London. Series B: Biological Sciences, 271(suppl_4), S131-S133.        
Curtis, V., & Biran, A. (2001). Dirt, disgust, and disease: Is hygiene in our genes? Perspectives in biology and medicine, 44(1), 17-31.  
Faulkner, J., Schaller, M., Park, J. H., & Duncan, L. A. (2004). Evolved disease-avoidance mechanisms and contemporary xenophobic attitudes. Group Processes & Intergroup Relations, 7(4), 333-353.         
Gassen, J., Prokosch, M. L., Makhanova, A., Eimerbrink, M. J., White, J. D., Leyva, R. P. P., . . . Maner, J. K. (2018). Behavioral immune system activity predicts downregulation of chronic basal inflammation. PloS one, 13(9).     
Gretz, M. R., & Huff, M. J. (2019). Did you wash your hands? Evaluating memory for objects touched by healthy individuals and individuals with contagious and noncontagious diseases. Applied Cognitive Psychology, 33(6), 1271-1278.         
Huang, J. Y., Sedlovskaya, A., Ackerman, J. M., & Bargh, J. A. (2011). Immunizing against prejudice: Effects of disease protection on attitudes toward out-groups. Psychological Science, 22(12), 1550-1556.        
Ji, T., Tybur, J. M., & van Vugt, M. (2019). Generalized or origin-specific out-group prejudice? The role of temporary and chronic pathogen-avoidance motivation in intergroup relations. Evolutionary Psychology, 17(1), 1474704919826851.      
Kurzban, R., & Leary, M. R. (2001). Evolutionary origins of stigmatization: the functions of social exclusion. Psychological bulletin, 127(2), 187.      
Kwagala, S. G., & Hares, S. (2019). People living with HIV’s experiences of HIV-related stigmatization and discrimination.: A literature study.
Li, S., Wang, Y., Xue, J., Zhao, N., & Zhu, T. (2020). The impact of COVID-19 epidemic declaration on psychological consequences: a study on active Weibo users. International journal of environmental research and public health, 17(6), 2032.   
Mitzel, L. D., Vanable, P. A., & Carey, M. P. (2019). HIV-related stigmatization and medication adherence: Indirect effects of disclosure concerns and depression. Stigma and Health, 4(3), 282.         
Mortensen, C. R., Becker, D. V., Ackerman, J. M., Neuberg, S. L., & Kenrick, D. T. (2010). Infection breeds reticence: The effects of disease salience on self-perceptions of personality and behavioral avoidance tendencies. Psychological Science, 21(3), 440-447.
Murray, D. R., Prokosch, M. L., & Airington, Z. (2019). PsychoBehavioroimmunology: connecting the behavioral immune system to its physiological foundations. Frontiers in psychology, 10.           
Murray, D. R., & Schaller, M. (2016). The behavioral immune system: Implications for social cognition, social interaction, and social influence Advances in experimental social psychology (Vol. 53, pp. 75-129): Elsevier
Oaten, M., Stevenson, R. J., & Case, T. I. (2009). Disgust as a disease-avoidance mechanism. Psychological bulletin, 135(2), 303.           
Park, J. H., Faulkner, J., & Schaller, M. (2003). Evolved disease-avoidance processes and contemporary anti-social behavior: Prejudicial attitudes and avoidance of people with physical disabilities. Journal of Nonverbal behavior, 27(2), 65-87.  
Polák, J., Landová, E., & Frynta, D. (2019). Undisguised disgust: a psychometric evaluation of a disgust propensity measure. Current Psychology, 38(3), 608-617.     
Prokosch, M. L., Gassen, J., Ackerman, J. M., & Hill, S. E. (2019). Caution in the time of cholera: Pathogen threats decrease risk tolerance. Evolutionary Behavioral Sciences.          
Regenbogen, C., Axelsson, J., Lasselin, J., Porada, D. K., Sundelin, T., Peter, M. G., . . . Olsson, M. J. (2017). Behavioral and neural correlates to multisensory detection of sick humans. Proceedings of the National Academy of Sciences, 114(24), 6400-6405.      
Šantić, A., Šantić, K., Radoja, I., & Jelinčić, I. (2020). Stigmatization of Patients With Viral Infections and Mass Psychogenic Illness. Southeastern European Medical Journal: SEEMEDJ, 4(1), 1-13.      
Schaller, M. (2006). Parasites, behavioral defenses, and the social psychological mechanisms through which cultures are evoked. Psychological Inquiry, 17(2), 96-101.    
Schaller, M., Miller, G. E., Gervais, W. M., Yager, S., & Chen, E. (2010). Mere visual perception of other people’s disease symptoms facilitates a more aggressive immune response. Psychological Science, 21(5), 649-652.  
Schaller, M., & Park, J. H. (2011). The behavioral immune system (and why it matters). Current directions in psychological science, 20(2), 99-103.
Shakhar, K. (2019). The inclusive behavioral immune system. Frontiers in psychology, 10.      
Terrizzi Jr, J. A., Clay, R., & Shook, N. J. (2014). Does the behavioral immune system prepare females to be religiously conservative and collectivistic? Personality and Social Psychology Bulletin, 40(2), 189-202.     
Toth, A. L. (2019). Shamanistic Beliefs and the Behavioral Immune System. California State University, Fullerton.  
van Leeuwen, F., & Petersen, M. B. (2018). The behavioral immune system is designed to avoid infected individuals, not outgroups. Evolution and Human Behavior, 39(2), 226-234.           
Wouters, E., Sommerland, N., Masquillier, C., Rau, A., Engelbrecht, M., Van Rensburg, A. J., . . . Van Damme, W. (2020). Unpacking the dynamics of double stigma: how the HIV-TB co-epidemic alters TB stigma and its management among healthcare workers. BMC Infectious Diseases, 20(1), 106.           
Zakrzewska, M., Olofsson, J. K., Lindholm, T., Blomkvist, A., & Liuzza, M. T. (2019). Body odor disgust sensitivity is associated with prejudice towards a fictive group of immigrants. Physiology & behavior, 201, 221-227.       
Zakrzewska, M. Z., Liuzza, M. T., Lindholm, T., Blomkvist, A., Larsson, M., & Olofsson, J. K. (2020). An Overprotective Nose? Implicit Bias Is Positively Related to Individual Differences in Body Odor Disgust Sensitivity. Frontiers in Psychology, 11, 301.    
Zebrowitz, L. A., Fellous, J.-M., Mignault, A., & Andreoletti, C. (2003). Trait impressions as overgeneralized responses to adaptively significant facial qualities: Evidence from connectionist modeling. Personality and social psychology review, 7(3), 194-215.