The Relationship of Depression with Treatment Adherence in Patients with Multiple Sclerosis (MS): The Moderating Role of Sleep Quality

Sadeghi-Firoozabadi, Vahid; Khosh, Haniyeh; Dehghani, Mohsen; Khatibi, Ali; Nasser Moghaddasi, AbdolReza; Abdolmanafi, Vahid

doi:10.30473/ijohp.2025.71290.1359

Document Type : research

Authors

¹ Assistant Professor, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

² 1. Master of Clinical Psychology, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

³ 3. Associate Professor, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

⁴ 4. Postdoctoral Researcher, Spinal Pain Rehabilitation Centre, School of Sport, Exercise and Rehabilitation Sciences, College of Environmental and Life Sciences, University of Birmingham, Birmingham, UK.

⁵ Assistant Professor, Neurologist, MS Research Center, Neuroscience Research Institute, Tehran University of Medical Sciences, Tehran, Iran

⁶ Master of Clinical Psychology, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran

https://doi.org/10.30473/ijohp.2025.71290.1359

Abstract

Objective: This research was conducted to study the role of sleep quality moderators in the relationship between depression and treatment compliance.
Method: The research design was descriptive and correlational, and the research population included all patients with multiple sclerosis living in Tehran. 229 subjects with Multiple Sclerosis were selected in a convenient method, and they were asked to answer Morinsky's treatment compliance, Petersburg sleep quality, and Beck's depression questionnaires using the pencil and paper method.
Results: Evidence of the predictive role of depressive symptoms for poor adherence to treatment in patients with multiple sclerosis was found. In addition, evidence of the predictive role of sleep quality in treatment adherence was found, but its mediating role in the relationship between depression and treatment adherence was not found.
Conclusion: The findings indicated the importance of depression symptoms and sleep quality in the treatment compliance of multiple sclerosis patients. Considering the importance of treatment compliance in the prognosis of the disease, it is suggested that doctors consider this issue to formulate treatment plans to target cognitive and emotional problems parallel to the main treatment of the disease and thereby increase treatment compliance.

Keywords

Main Subjects

Chronic diseases such as cancer, diabetes, AIDS, cardiovascular, MS, etc.

Article Title [Persian]

رابطه افسردگی با تبعیت از درمان در بیماران مبتلا به مولتیپل اسکلروزیس (MS): نقش تعدیل کننده کیفیت خواب

Authors [Persian]

وحید صادقی فیروزآبادی ¹
حانیه خوش ²
محسن دهقانی ³
علی خطیبی ⁴
عبدالرضا ناصر مقدسی ⁵
وحید عبدالمنافی ⁶

¹ Assistant Professor, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

² 1. Master of Clinical Psychology, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

³ 3. Associate Professor, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.

⁵ Assistant Professor, Neurologist, MS Research Center, Neuroscience Research Institute, Tehran University of Medical Sciences, Tehran, Iran

⁶ Master of Clinical Psychology, Department of Clinical and Health Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran

Abstract [Persian]

هدف: این پژوهش با هدف بررسی نقش تعدیل کننده کیفیت خواب در رابطه بین افسردگی و انطباق با درمان انجام شد. روش: طرح پژوهش توصیفی و از نوع همبستگی بود و جامعه شامل کلیه بیماران مبتلا به مولتیپل اسکلروزیس ساکن تهران بود. 229 آزمودنی مبتلا به مولتیپل اسکلروزیس به روش در دسترس انتخاب شدند و از آنها خواسته شد به پرسشنامه های انطباق درمانی مورینسکی، کیفیت خواب پترزبورگ و افسردگی بک به روش مداد و کاغذ پاسخ دهند. یافته‌ها: شواهدی از نقش پیش‌بینی‌کننده علائم افسردگی در پایبندی ضعیف به درمان در بیماران مبتلا به مولتیپل اسکلروزیس یافت شد. علاوه بر این، شواهدی مبنی بر نقش پیش‌بینی‌کننده کیفیت خواب در تبعیت از درمان یافت شد، اما نقش میانجی آن در رابطه بین افسردگی و تبعیت از درمان یافت نشد. نتیجه‌گیری: یافته‌ها حاکی از اهمیت علائم افسردگی و کیفیت خواب در انطباق با درمان بیماران مولتیپل اسکلروزیس است. با توجه به اهمیت انطباق درمان در پیش آگهی بیماری، پیشنهاد می‌شود که پزشکان با توجه به این موضوع، برنامه‌های درمانی را برای هدف قرار دادن مشکلات شناختی و عاطفی به موازات درمان اصلی بیماری و در نتیجه افزایش انطباق با درمان، تدوین کنند.

Keywords [Persian]

تبعیت درمانی
افسردگی
ام اس
کیفیت خواب
سلامتی

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The Relationship of Depression with Treatment Adherence in Patients with Multiple Sclerosis (MS): The Moderating Role of Sleep Quality

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Volume 7, Issue 4 - Serial Number 22November 2024

Volume 7, Issue 4 - Serial Number 22
November 2024