Increasing the quality of sleep and life by brain electrical stimulation in patients with painful diabetic neuropathy

Alipour, Ahmad; Mohammadi, Roghayeh

doi:10.30473/ijohp.2023.65404.1274

Document Type : research

Authors

Ahmad Alipour ¹
Roghayeh Mohammadi ²

¹ Professor of Payame Noor University

² Postdoctoral Researcher in Clinical Neuropsychology, Payam Noor University, Tehran, Iran (Corresponding Author)

https://doi.org/10.30473/ijohp.2023.65404.1274

Abstract

Objective: Painful diabetic neuropathy is a major complication of chronic diabetes with a significant negative impact
on the quality of sleep and quality of life in diabetic patients. This study was conducted to determine the single and
combined effect of the primary motor cortex (M1) and left Dorsolateral prefrontal cortex (L- DLPFC/ F3) anodic
transcranial direct current stimulation (tDCS) in improving sleep quality and quality of life in type 2 diabetes patients
with neuropathic pain.
Method: The current study was a four-group double-blind randomized clinical trial. The statistical population consisted
of all patients with type 2 diabetes aged 45 to 65 years, who were members of the Bonab Diabetes Association in
2022 and identified as having neuropathic pain by specialists. The research sample was 48 people selected through
the purposeful sampling method and randomly assigned into three experimental groups and one sham control group.
Patients in four groups received their respective interventions for 12 sessions, three times a week. The data collection
was done using the Pittsburgh Sleep Quality Index (PSQI) and the 36-Item Short Form Quality of Life questionnaire
(SF-36).
Results: According to the findings, only the stimulation of M1 and F3 areas was effective in improving the sleep
quality of diabetic patients. In terms of increasing quality of life, the effect of combined treatment (stimulation of
both M1 and F3 areas) was significantly higher than the F3 area stimulation and sham stimulation groups. Also, the
observed effect remained stable until the 3-month follow-up stage.
Conclusion: According to the results of this research, neuropsychological rehabilitation through electrical stimulation
of the M1 and F3 areas of the brain was supported to improve the sleep quality and the quality of life of diabetic
neuropathy patients.

Keywords

Article Title [Persian]

افزایش کیفیت خواب و زندگی با تحریک الکتریکی مغز در بیماران دارای دردهای نوروپاتیک دیابتی

Authors [Persian]

احمد علی پور ¹
رقیه محمدی ²

¹ استاد روان شناسی، دانشگاه پیام نور، تهران، ایران

² پژوهشگر پسادکتری عصب روان شناسی بالینی-دانشگاه پیام نور-

Abstract [Persian]

دردهای نوروپاتی دیابتی که از عوارض شایع دیابت مزمن هستند، تأثیر منفی زیادی بر کیفیت خواب و کیفیت زندگی مبتلایان به دیابت دارند. بنابراین، این پژوهش با هدف تعیین اثر خالص و ترکیبی tDCS آندی ناحیه M1 و ناحیه F3 در بهبود کیفیت خواب و کیفیت زندگی در مبتلایان به دیابت نوع 2 دارای دردهای نوروپاتیک انجام گرفت. پژوهش حاضر، یک کــار آزمــایی بــالینی تصــادفی چهار گروهـــی دو ســر کور می باشــد. جامعه آماری پژوهش حاضر، کلیه بیماران 45 تا 65 ساله مبتلا به دیابت نوع 2 عضو انجمن دیابت شهرستان بناب در زمستان 1400 و بهار 1401 بودند که توسط متخصصان، دارای دردهای نوروپاتیک شناسایی شده بودند. نمونه‌ پژوهش 48 تن بودند که به روش هدفمند انتخاب شدندو بطور تصادفی در 3 گروه آزمایشی و 1 گروه کنترل-شم جایگزین شدند. بیماران گروههای 4 گانه به مدت 12 جلسه، سه بار در هفته، مداخلات مربوط به خود را اخذ کردند. ابزار گردآوری اطلاعات، مقیاس استاندارد کیفیت خواب پیتزبورگ (P.S.I.Q) و پرسشنامه کیفیت زندگی ۳۶ سوالی (SF-36) بود. طبق یافته ها فقط تحریک هر دو ناحیه M1 و F3 در بهبود کیفیت خواب بیماران دیابتی، موثر واقع شده بود. در مورد افزایش کیفیت زندگی نیز، اثر درمان ترکیبی (تحریک هر دو ناحیه M1 و F3) بطور معناداری از تحریک ناحیه F3 و تحریک شم، بیشتر بود. از طرفی، اثر دیده شده تا مرحله پیگیری 3 ماهه، پایدار مانده بود. با توجه به نتایج این پژوهش، توانبخشی عصب روان شناختی از طریق تحریک الکتریکی نواحی M1 و F3 مغز، برای ارتقا کیفیت خواب و زندگی مبتلایان به دردهای نوروپاتی دیابتی، حمایت می شود.

Keywords [Persian]

درد نوروپاتی دیابتی
کیفیت خواب
کیفیت زندگی
tDCS

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Increasing the quality of sleep and life by brain electrical stimulation in patients with painful diabetic neuropathy

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Volume 6, Issue 1 - Serial Number 15March 2023Pages 27-40

Volume 6, Issue 1 - Serial Number 15
March 2023
Pages 27-40